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Ibutamoren, MK 677 heightens the appetite, so it is normal for users to increase the intake of calories beyond what they can burn. Consumption of Ibutamoren, MK677 leads to fluid retention,which in turn may result in mild edema (swelling) of the lower extremities, rad 140 sode effects. In the long term, the use of this product may lead to insulin resistance, a pathological condition directly related to higher blood sugar levels and possibly type 2 diabetes. Ibutamoren, MK677 could also increase blood pressure and cause heart failure, although the study that yielded these results included elderly patients who already suffered from these ailments. It is important to keep all of these risks in mind when evaluating the risks and benefits of SARM usage, since they are in a decidedly different category compared to your typical sports performance supplement, rad 140 sode effects.